We investigate these topics …
- How behavioral state affects the flow of information through neural circuits in:
- The neural circuits that mediate active avoidance behavior
… using the these methods …
- Electrophysiology
- whole-cell recordings
- single-unit recordings
- field potentials
- EMG
- Neuropharmacology
- Optogenetics
- DREADDS
- Fiber photometry
- Microdialysis
- Behavioral conditioning
- Video tracking
- Histology
- single cell reconstructions
- AAV injections and cannula tracing
… in mice that are under these conditions …
- Freely behaving (tethered)
- Head-fixed
- Anesthetized
- Brain slices (in vitro)
Rigor is an important consideration in our work. Our experiments and analyses are automated (coded), so there are fewer confounding variables.